Biological properties of Zn–0.04Mg–2Ag: a new degradable zinc alloy scaffold for repairing large-scale bone defects
نویسندگان
چکیده
منابع مشابه
A new strategy for repairing large bone defects using an interventional micro-circulation system
Repairing large bone defects remains a difficult clinical problem because of the variability in the defects. The traditional methods, such as autograft, allograft bone and biological filler material transplantation are still facing difficulties in clinical application nowadays. Tissue engineering technology has the potential to solve this problem, and it has thus become a popular research topic...
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Background: In the present study, a tissue engineered silk fibroin (SF) scaffold containing simvastatin-loaded silk fibroin nanoparticles (SFNPs) were used to stimulate the regeneration of the defected bone. Methods: At first, the porous SF scaffold was prepared using freeze-drying. Then simvastatin-loaded SFNPs were made by dissolvation method and embedded in the SF scaffold. Afterwards, the ...
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The hydrophilic, conducting, biocompatible and porous scaffolds were designed using poly(2-hydroxy ethyl methacrylate)-co-poly(N-isopropylacrylamide)-co-poly(ε-caprolactone) (P(HEMA-b-NIPAAm-b-CL))/polyaniline (PANI) for the osteoblast applications. To this end, the PHEMA and P(HEMA-b-NIPAAm) were synthesized via reversible addition of fragmentation chain transfer (RAFT) polymerization, and in ...
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We prepared a bone scaffold material comprising a PLGA/β-TCP core and a Type I collagen cladding, and recombined it with bone marrow stroma stem cells (BMSCs) to evaluate its potential for use in bone tissue engineering by in vivo and in vitro experiments. PLGA/β-TCP without a cladding was used for comparison. The adherence rate of the BMSCs to the scaffold was determined by cell counting. Cell...
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BACKGROUND Although three-dimensional (3D) β-tricalcium phosphate (β-TCP) scaffolds serve as promising bone graft substitutes for the segmental bone defect treatment, no consensus has been achieved regarding their optimal 3D architecture. METHODS In this study, we has systematically compared four types of β-TCP bone graft substitutes with different 3D architectures, including two types of por...
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ژورنال
عنوان ژورنال: Journal of Materials Research and Technology
سال: 2021
ISSN: 2238-7854
DOI: 10.1016/j.jmrt.2021.05.096